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Sr Manager, Systems Design Engineering

8-10 Years
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Job Description

Job Description :

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Senior Manager, Systems Engineering - qPCR Platforms

About the Role

In the role of Systems Engineering Senior Lead, you'll be the architect and technical owner of our next-generation qPCR systems. You'll bring together hardware, software, assays, algorithms, and consumables into one cohesive platform - driving innovation from concept to commercialization!

This role blends strategic leadership with hands-on technical depth. You'll lead a team of architects and engineers, partner with business and product leaders, and ensure every system we build is reliable, scalable, and ground-breaking for our customers.

What You'll Do

Own the System Architecture

  • Define and own the system architecture for integrated qPCR platforms spanning hardware, software, assay, and algorithm development.

  • Translate user needs and business goals into clear system requirements that balance performance, usability, manufacturability, and compliance.

  • Lead design trade-offs and technical risk analyses to ensure robustness and scalability.

  • Champion the architectural vision from early concept through final commercial product.

Lead multi-functional Integration

  • Partner closely with Product Management, Operations, Assay, Software, and Algorithm teams to align technology and product strategies.

  • Drive system-level integration, ensuring seamless collaboration across fields and geographies.

  • Communicate complex technical decisions and trade-offs to senior collaborators with clarity and influence.

  • Work hand-in-hand with Manufacturing, Quality, and Service teams to ensure design choices enable smooth scale-up and long-term reliability.

Drive Innovation and Execution

  • Serve as the hands-on technical authority for system definition, integration, and root-cause analysis.
  • Guide technology down-selection, system verification, and early-stage prototyping efforts.
  • Advance systems engineering practices - adopting model-based methods, simulation tools, and data-driven approaches.
  • Champion new technologies and ideas that push the boundaries of what's possible in qPCR instrumentation.

Build and Develop the Team

  • Recruit, mentor, and empower an extraordinary systems engineering team.

  • Create a culture that values innovation, rigor, and collaborative problem-solving.

  • Provide mentorship and growth opportunities for emerging technical leaders.

  • Shape and scale systems engineering excellence across the broader R&D organization.

What You Bring

  • 8+ years of experience in systems engineering or multi-functional product development for life science or diagnostic instruments.

  • Proven record of leading system integration across hardware, software, and consumables - from concept to launch.

  • Demonstrated success managing and developing successful technical teams.

  • Strong experience working in regulated environments (ISO 13485, FDA QSR, CE-IVD).

  • Ability to partner strategically with Product Management and business leaders to translate vision into executable roadmaps.

  • Deep understanding of systems engineering principles and broad technical fluency across mechanical, electrical, software, and assay domains.

  • Excellent communication and influencing skills comfortable communicating complex ideas to both engineers and executives.

Education

  • Bachelor's, Master's, or Ph.D. in Engineering (Mechanical, Electrical, Systems, or Software) or Applied Physics advanced degree preferred.

About Company

Thermo Fisher Scientific Inc. is an American supplier of scientific instrumentation, reagents and consumables, and software services. Based in Waltham, Massachusetts, Thermo Fisher was formed through the merger of Thermo Electron and Fisher Scientific in 2006. Thermo Fisher Scientific has acquired other reagent, consumable, instrumentation, and service providers, including: Life Technologies Corporation (2013), Alfa Aesar (2015),Affymetrix (2016),FEI Company (2016), BD Advanced Bioprocessing (2018),and PPD (2021).
As of 2017, the company had a market capitalization of $21 billion and was a Fortune 500 company. Annual revenue in 2021 was US$39.21 billion.
In March 2020, Thermo Fisher Scientific received emergency use authorization from the FDA for a test for SARS-CoV-2 to help mitigate the COVID-19 pandemic.

Job ID: 135671005

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