Senior Scientist (Mid-Size Molecule Unit) - Chemistry

Chugai Pharmabody Research Pte. Ltd. (CPR) was established in Singapore as a wholly-owned subsidiary of Chugai Pharmaceutical Co., Ltd (Chugai), a member of Roche group, in January 2012 and started operations on July 2, 2012. Located at Biopolis in Singapore, it aims to generate new antibody drugs based on Chugai's proprietary antibody engineering technologies, such as recycling antibody, sweeping antibody, bispecific antibody, various Fc engineered antibodies, cyclic peptides and other new antibody engineering technologies that are under development.

Position - Senior Scientist in Mid-size Molecule Unit

CPR is seeking a Senior Scientist with expertise in drug discovery utilizing novel organic chemistry and biotechnology platform. You will leverage your passion and creativity to lead mid-size molecule projects through the identification of drug candidates, collaborating with other multi-disciplinary teams to achieve a milestone of a project. The candidate will play a key role in driving our innovative drug discovery projects and cutting-edge technology development through the fusion of chemistry and biotechnology.

Key Responsibilities

• Hit peptide identification from screening with our Mid-size library.
• Lead candidates creation through optimization of hit peptide.
• Novel peptide screening technology development.
• Propose and lead drug discovery project.

Job Requirements

The applicant should be highly skilled in at least one of the following areas:

• Organic chemistry.
• Peptide chemistry or nucleic acid chemistry, including solid phase synthesis.
• Medicinal chemistry in small molecules and/or mid-size molecules.
• Chemical biology for protein structure and mode of action analysis.

Qualifications

• Completed and be awarded with a relevant Ph.D. degree in Organic Chemistry/Medicinal Chemistry/Biochemistry/Chemical Biology with 1-2 years of working experience in related fields.
• Able to demonstrate technical expertise in areas which may include peptide chemistry and nucleotide chemistry and as evidenced by projects, presentations, or peer-reviewed scientific publications.
• Scientists with strong passion in medical science for creating and delivering innovative drugs to society which leads to saving patients suffering from unmet medical needs are highly desired.
• Familiarity or having prior work experience in precise experiments with great attention to details (i.e., comparable attention required for aseptic manipulation) will be a plus.
• Good command of spoken and written English, excellent organizational and communication skills, team player mindset, as well as the ability to multi-task.

Interested applicants are invited to email their detailed resume, as well as their qualifications, availability, current and expected salary to:[Confidential Information]

For more information regarding our Company, you may refer to our website at:

We regret that only short-listed candidates will be notified