Research Officer (DMODL)

You will support the progress of research studies under the Head and Neck Cancer/Nasopharyngeal Cancer Program. You will perform a variety of research activities including but not limited to the following:

1. Tissue Logistics and Processing:

- Collection and processing of biological samples (e.g. FFPE, Tissue, Blood).

- Maintain proper tracking of samples, updating of inventories and databases for respective studies.

- Nuclei acid extraction from biological samples.

- Coordinate the submission of biological samples to external partners.

2. Cell culture and Molecular assays:

- Generation and maintenance of patient-derived cell lines and/or organoids.

- Perform molecular biology assays e.g. nuclei acid extraction, qPCR, cloning, library preparation, sequencing.

- Perform cell biology assays e.g. drug treatment, cell migration, western blot.

- Participate in experimental troubleshooting and assay optimization.

3. Histology and Microscopy:

- Generation of FFPE tissue blocks and tissue sectioning.

- Staining of biological samples by immunohistochemistry or immunofluorescence.

- Image acquisition and analysis.

4. Perform tasks and support all aspects of the research project:

- Perform literature reviews when required.

- Plan and execute experiments for the assigned studies.

- Monitor and document accurate records of experimental data and observations.

- Evaluate and interpret collected data for oral presentations and scientific manuscripts.

- Report and summarize experimental results and research findings in meetings.

- Support lab and administrative duties in lab operations, e.g. procurement, equipment maintenance, inventories and lab maintenance etc.

- Support and maintain safety documentation and compliance of the lab.

- Lead and mentor junior staff and students in sample processing, experiments, data analysis, and database updates (Senior Research Officer).

5. Perform other related duties:

- Other ad-hoc duties as assigned.

Requirements:

- Bachelor/Master of Science degree in related technical discipline (biology, cell biology, biomedical science, biochemistry or molecular biology).

- Minimum 1 year experience with tissue culture (especially primary cultures) and molecular techniques.

- Experience with wet-lab handling of patient-derived samples is preferred.

- Strong technical and wet lab skills.

- Team player with excellent communication skills and the ability to work independently.

- Responsible, diligent, possess initiative to complete tasks and projects assigned.

- Highly motivated to learn with a genuine interest in cancer research.

- Able to undertake independent research progressively.