Research Assistant/Associate, Cardiometabolic Medicine [LKCMedicine]

The Lee Kong Chian School of Medicine (LKCMedicine) trains doctors who put patients at the centre of their exemplary care. The School, which offers both undergraduate and graduate programmes, is named after local philanthropist Tan Sri Dato Lee Kong Chian. Established in 2010 by Nanyang Technological University, Singapore, in partnership with Imperial College London, LKCMedicine aims to be a model for innovative medical education and a centre for transformative research. The School's primary clinical partner is the National Healthcare Group, a leader in public healthcare recognised for the quality of its medical expertise, facilities and teaching. The School is transitioning to an NTU medical school ahead of the 2028 successful conclusion of the NTU-Imperial partnership to set up a Joint Medical School. In August 2024, we welcomed our first intake of the NTU MBBS programme, that has been recently enhanced to include themes like precision medicine and Artificial Intelligence (AI) in healthcare, with an expanded scope in the medical humanities. Graduates from the five-year undergraduate medical degree programme will have a strong understanding of the scientific basis of medicine, with an emphasis on technology, data science and the humanities.

Assistant Professor Lynn Yap is looking for a motivated Research Assistant/ Research Associate to join her laboratory at the Lee Kong Chian School of Medicine (Novena), a medical school in Nanyang Technological University (NTU).

A/Prof Yap laboratory is working on the field of regenerative cardiology and metabolic disorders, where the team is interested in the basic and translational cardiometabolic research. The laboratory is focusing on regenerative cardiology using stem cell therapy to investigate cardio-immunology regeneration. We work with pluripotent stem cells and cardiovascular progenitor-mediated repair of myocardial infarction in small (rodents) and large (pigs) animal models. When transplanted into the animals, these progenitor cells engrafted, long-term survived and avoided ventricular arrhythmia in the animal. Therefore, providing a potential cellular therapy product for ischemic heart disease patients. In addition, we are interested in uncovering the molecular mechanism of cardiac regeneration, human graft maturation and host immunology in the heart using disruptive technologies and inventions.

Lynn Yap's laboratory is pursuing medical innovations by integrating science, engineering and technology to positively impact patients lives. Therefore, this role will provide an exciting opportunity for the individual to learn and experience collaborative academic/industry research and play an important role in impacting patients lives.

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We are looking for a motivated Research Assistant to join a collaborative project by Assistant Professor Lynn Yap (Lee Kong Chian School of Medicine, Novena campus). The role will focus on performing cellular and molecular experiments and animal models.

Responsibilities:

• Conduct accurate monitoring, documenting and reporting of experimental results

• Assist in experiments including stem cell culture, western blotting, molecular biology, microscopy, histology, flow cytometry and bioinformatics.

• Assist in large animal study and IACUC revisions

• Assist in the general upkeep of laboratory needs, maintain safety protocols, risk assessments, lab audits and management of inventories

• Perform other related duties related to the work describe herein or assigned by the supervisor

Requirements:

• Bachelor's or Master's degree in Sciences/Life Sciences/ Data Science/Immunology with at least 2 year of work experience in a research environment.

• Good written and oral communication skills

• Demonstrated knowledge, skills, and expertise in supporting various research activities includingmolecular and cell biology, histology, flow cytometry and microscopy.

• Experience with stem cell biology and immunology.

• Strong interpersonal skills and astrong team player who is organized, energetic, open-minded, highly motivated, and able to multi-task and work collaboratively in a diverse team.

• RCULA certification and experience with animal studies will be an advantage.

• Entry level candidates are welcome to apply