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Medical Laboratory Technologist_Molecular Diagnostics (Genetics & Genomics)

Medical Laboratory Technologist_Molecular Diagnostics (Genetics & Genomics)

nuhs@home
1-2 Years
Not Disclosed
  • Posted 39 minutes ago
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Job Description

Job ID: 10564

Job Function: Allied Health

Institution: National University Hospital

To perform routine clinical molecular diagnostic testing and related laboratory activities to deliver high-quality, accurate and timely diagnostic services for patient care. The incumbent will support the day-to-day operations of a clinical molecular diagnostics laboratory, participate in quality and continuous improvement initiatives, and have opportunities to gain exposure to emerging genetic and genomic testing technologies within a CAP-accredited clinical laboratory.

Job Responsibilities

  • Receive, accession and assess clinical specimens for suitability for molecular diagnostic testing according to established laboratory criteria.
  • Perform routine molecular diagnostic procedures, including but not limited to:
    • Nucleic acid extraction and quantification
    • PCR and real-time PCR assays
    • Sanger sequencing
    • NGS library preparation and sequencing workflows
    • Other molecular diagnostic techniques as required by the laboratory
  • Operate the Laboratory Information System (LIS) for test registration, result entry, result verification and result enquiry.
  • Perform laboratory testing in accordance with approved SOPs, quality standards and turnaround-time requirements.
  • Review assay quality metrics and quality control results and escalate test failures, discrepancies or non-conformities to senior staff where appropriate.
  • Ensure critical and urgent test results are communicated according to laboratory policies.
  • Resolve routine enquiries from clinicians, healthcare professionals and other stakeholders.
  • Perform routine preventive maintenance and basic troubleshooting of molecular diagnostic instruments and equipment.
  • Maintain accurate and complete laboratory records, worksheets and documentation in compliance with accreditation requirements.
  • Assist in inventory management, stock monitoring and procurement of laboratory consumables and reagents.
  • Participate in quality assurance activities, proficiency testing programmes and continuous quality improvement initiatives.
  • Assist with validation and implementation activities for new reagents, equipment and assays when required.
  • Train and guide trainees, students and newly appointed staff in routine laboratory procedures.
  • Report adverse incidents, safety concerns and quality events to supervisors promptly.
  • Assist with internal audits and accreditation activities.
  • Ensure compliance with CAP, ISO15189, laboratory safety policies and regulatory requirements.
  • Uphold NUHS Core Values and comply with departmental workplace practices.
  • Assist with verification, validation and performance evaluation studies for new molecular diagnostic assays.
  • Assist in drafting, reviewing and updating SOPs, work instructions and laboratory forms.
  • Participate in department projects related to workflow optimisation, quality improvement and service enhancement.
  • Support implementation of new molecular and genomic testing services as required.
  • Assist with administrative tasks related to laboratory operations.
  • Cover duties of Senior Medical Technologist when required.
Requirements

  • Bachelor of Science (BSc) or equivalent in Medical Laboratory Science, Biomedical Science, Molecular Biology, Genetics, Life Sciences or related disciplines.
  • Preferably 1-2 years of experience in a clinical laboratory setting.
  • Experience in molecular diagnostic testing is preferred.
  • Exposure to PCR, real-time PCR, Sanger sequencing and/or NGS workflows would be advantageous.
  • Good understanding of molecular biology principles and molecular diagnostic techniques.
  • Good laboratory skills and ability to follow established protocols accurately.
  • Familiarity with Laboratory Information Systems and laboratory quality management systems.
  • Basic knowledge of genetic and genomic testing workflows would be advantageous

More Info

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Key Skills

Nucleic acid extraction and quantification

Laboratory quality management systems

PCR and real-time PCR assays

NGS library preparation and sequencing workflows

Laboratory Information System (LIS)

Sanger sequencing

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