Executive / Senior Executive, Bioinformatician, STCC

Overview

The Consortium for Clinical Research and Innovation, Singapore (CRIS) brings together five national R&D, clinical translation and service programmes to advance clinical research and innovation for Singapore, and establish important capabilities for a future-ready healthcare system.

The Business Entities under CRIS include:

• Singapore Clinical Research Institute (SCRI)
• National Health Innovation Centre (NHIC)
• Advanced Cell Therapy and Research Institute, Singapore (ACTRIS)
• Precision Health Research, Singapore (PRECISE)
• Singapore Translational Cancer Consortium (STCC)

Together, CRIS makes a positive difference to Singapore patients and researchers by ensuring that these clinical research platforms and programmes are at the cutting edge of capability development and innovation. If you are as passionate as we are in clinical trials and research, we want you!

STCC

The Singapore Translational Cancer Consortium (STCC) is a nationally coordinated consortium to synergise cancer research capabilities in Singapore. Established in 2020, STCC brings together unmatched basic, clinical and translational talent in Singapore to create globally significant peaks of excellence in selected Asian cancers. STCC's four joint platforms - Clinical Trials and Investigational Medicine Units, Cancer Databases and Tissue Banks, Translational Research Integration and Support, and Business Intelligence and Development Unit - provide an enabling research and innovation environment driven to foster translational research with meaningful outcomes for society. We currently have the following opening and would like to invite you to be part of an ongoing and dynamic team.

STCC's five joint platforms - Cancer Clinical Trials and Investigational Medicine Units, Cancer Databases and Tissue Banks, Translational Research Integration and Support, Business Intelligence and Development, and Impact and Population Health - provide an enabling research and innovation environment driven to foster translational research and meaningful outcomes for society.

Through collaborative relationships with our partner institutions [comprising of National Cancer Centre Singapore (NCCS), National University Cancer Institute, Singapore (NCIS), National University Hospital (NUH), National University of Singapore (NUS) and Tan Tock Seng Hospital (TTSH)], and by capitalizing on the strengths of industry and academia, STCC is uniquely poised to develop initiatives that are aligned with Singapore's goals in value-based healthcare innovation and economic value creation.

STCC is a business unit of the Consortium for Clinical Research and Innovation, Singapore (CRIS), and is supported by the National Research Foundation, Singapore (NRF) and the Singapore Ministry of Health through the National Medical Research Council (NMRC) Office, MOH Holdings Pte Ltd.

What you will be working on

STCC's Translational Research Integration and Support platform provides a platform for molecular profiling of clinical samples for large-scale cancer research projects spanning across all major health clusters in Singapore. As a Bioinformatician, you will help to integrate molecular profiling data from various cancer cohorts and assist creation of a storage and sharing platform of research data. It will be a part of an ambitious nation-wide network driving academic and industry collaboration to develop new molecular biomarkers and anti-cancer agents. Ultimately, these efforts will aid improvement of cancer patient outcomes locally and globally.

The Role:

The Bioinformatician will be responsible for the duties and responsibilities listed below:

Primary Responsibilities and Duties

• Design and implement data analysis and integration pipelines to support research projects, ensuring robust quality control and comprehensive scientific reporting
• Curate and harmonise multi-omics datasets from diverse sources, maintaining data integrity
• Assist development and management of databases for clinical and molecular profiling data, with specific focus on cancer genomics
• Monitor and evaluate emerging analytical platforms and technologies, implementing best practices across projects
• Create and deploy interactive web portals and data visualisation applications
• Collaborate with multidisciplinary teams to ensure an end-to-end workflow with external organizations
• Serve as technical representative of the team in project meetings and stakeholder communications
• Undertake additional responsibilities as required by the role and team needs

What we are looking for

Qualification

• Bachelor's or Master's degree in Computational Biology, Bioinformatics, Medical Informatics, Computer Science, Engineering, Physical Sciences, Mathematics, Statistics, or equivalent relevant discipline

Experience

• Strong R/Python programming skills and knowledge of Unix-based systems
• Experience in database management and handling large-scale datasets
• Background in biomedical data analysis and interpretation
• Proven track record of delivering data analytics solutions for scientific projects
• Experience developing web portals and interactive visualisation applications (e.g., R Shiny) will be an advantage
• Knowledge of molecular biology, cancer biology, and tumour immunology will be an advantage

Skills

• Personal initiative and ability to work effectively independently as well as part of a team
• Flexibility and ability to multi-task and deliver quality work under tight timelines
• Strong analytical mindset with proven problem-solving capabilities
• Meticulous attention to detail
• Good interpersonal and communication skills

What you need to know

Successful candidate will be offered a 3-year renewable contract. We regret that only shortlisted candidates will be contacted. For more information about CRIS and the Business Entities, visit our websites below:

• CRIS -
• SCRI -
• NHIC -
• ACTRIS -
• PRECISE -
• STCC -

Join us in shaping the future of cancer research and impact in Singapore and the region.