Bioinformatics Scientist, Assay Design and Pipelines

Position Summary

We are seeking a skilled and motivated Bioinformatics Scientist to join our team, specializing in assay and content development for qPCR, dPCR, and CE technologies. The role focuses on delivering high-quality assays on schedule and contributing to the development and maintenance of computational pipelines, databases, and infrastructure to scale assay development. This position requires strong domain knowledge of genomics, PCR-based methods, and proficiency in bioinformatics pipeline development. You will convert biological questions into assay strategies and assign robust primer/probe sets. You will streamline workflows and optimize code for efficiency and scalability. Collaboration with other bioinformatics scientists, product management, and customer support colleagues is essential.

Primary Responsibilities

• Design, develop, and optimize qPCR assays for various applications, including gene expression, genotyping, copy number analysis, and pathogen detection.
• Analyze and interpret complex genomic and sequence data to support target selection and assay development.
• Develop, maintain, and optimize bioinformatics pipelines and workflow automation for large-scale assay development.
• Maintain version-controlled repositories, documentation, and reproducibility across computational workflows.
• Participate in the publication or productization of developed algorithms, pipelines, or tools
• Prepare and present scientific reports and presentations to communicate findings and progress.

Required Qualifications

• Degree or Masters degree in bioinformatics, Computational Biology, Molecular Biology, Bioinformatics, or related fields. Preferred with 2+ years of relevant experience.
• Strong genomics & molecular biology domain knowledge in at least one of the domains in plants, mammalian, microbial, and oncology systems.
• Bioinformatics stack: IGV, BLAST, BWA/other aligners major databases (GenBank, Ensembl) experience across genomics, and quantitative data with strong analytical, problem-solving skills.
• Strong programming for scripting: Advanced Python
• Teaming & execution: excellent communication effective cross-functional collaboration able to work independently and manage multiple projects concurrently.

Preferred Qualifications

• Familiar in R, additional solid debugging. experience in C/C++/Java/Perl/Python/JavaScript/ReactJS
• Familiarity with workflow orchestration frameworks (Nextflow, Snakemake, Latch) or cloud computing and high-performance computing environments.
• Fundamental understanding of assay development, PCR chemistry
• Familiarity with cancer biology, genetics
• Experience with other assay development platforms, such as NGS, microarrays, etc.
• Hands-on experience with qPCR/dPCR instrumentation, assay optimization and validation.