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Staff Engineer, Systems Design Platform Engineering

5-10 Years
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Job Description

Job Description :

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Location: Singapore R&D

Business Unit: Genetic Sciences Division - qPCR/dPCR or MA Platforms

How You'll Make an Impact

As a Staff Systems Engineer in our Platform R&D team, you will play an important role in developing next-generation genetic analysis instrumentation. This is a hands-on role where you will integrate hardware, software, assays, and algorithms into systems that provide accuracy, and reliability for customers worldwide! You will partner across fields - from molecular biology to embedded systems - to translate user and business needs into innovative system builds.

What You Will Do

System Definition and Architecture

  • Translate customer and product requirements into clear system-level specifications and performance targets.
  • Develop system models and architecture frameworks spanning hardware, software, optics, and assay integration.
  • Conduct system analyses, trade-off studies, and feasibility assessments to inform build decisions.

Build and Integration

  • Lead system integration efforts for prototype and production genetic analyzer instrumentation.
  • Collaborate with electrical, mechanical, software, and assay teams to ensure robust subsystem interactions and signal integrity.
  • Perform verification testing, root-cause analysis, and system performance optimization.
  • Apply modeling and data-driven techniques (e.g., simulation, DOE, FMEA, RCA or equivalent experience) to evaluate and mitigate risks.

Innovation and Execution

  • Develop and validate new methods and architectures to improve efficiency, precision, and reliability.
  • Support early-stage prototyping, technology down-selection, and system scalability analysis.
  • Drive adoption of systems engineering standard methodologies, including model-based approaches and quantitative verification.

Collaboration Across Functions

  • Work closely with Product Management, Manufacturing, Quality, and Service to ensure system builds meet functional, operational, and regulatory needs.
  • Bring technical expertise during build reviews, risk assessments, and design transfers to manufacturing.

How You'll Get Here

Education & Experience

  • Bachelor's degree or equivalent experience in Engineering (Mechanical, Electrical, Systems, or Software) or Applied Physics with 10+ years of relevant industry experience or
  • Master's/Ph.D. with 5-7 years of experience developing life science instrumentation or diagnostic systems.

Technical Expertise

  • Proven track record in completing system integration and verification for complex electro-mechanical or optical instruments.
  • Familiarity with thermal control, optics, detection systems, statistical methods, fluidics, and signal processing in PCR or similar analytical systems.
  • Strong background in systems engineering methods: requirements management, modeling, FMEA, DOE, risk analysis, and reliability engineering.
  • Skilled in tools such as MATLAB, LabVIEW, Python, SolidWorks, and simulation/modeling environments.
  • Experience working in regulated environments (ISO 13485, FDA QSR, CE-IVD) preferred.

Interpersonal & Leadership Attributes

  • Self-directed engineer with a balance of analytical depth and practical execution.
  • Effective communicator across fields able to synthesize complex findings for technical and non-technical audiences.
  • Thrives in multi-functional, global R&D environments capable of influencing outcomes through technical credibility.

More Info

About Company

Thermo Fisher Scientific Inc. is an American supplier of scientific instrumentation, reagents and consumables, and software services. Based in Waltham, Massachusetts, Thermo Fisher was formed through the merger of Thermo Electron and Fisher Scientific in 2006. Thermo Fisher Scientific has acquired other reagent, consumable, instrumentation, and service providers, including: Life Technologies Corporation (2013), Alfa Aesar (2015),Affymetrix (2016),FEI Company (2016), BD Advanced Bioprocessing (2018),and PPD (2021).
As of 2017, the company had a market capitalization of $21 billion and was a Fortune 500 company. Annual revenue in 2021 was US$39.21 billion.
In March 2020, Thermo Fisher Scientific received emergency use authorization from the FDA for a test for SARS-CoV-2 to help mitigate the COVID-19 pandemic.

Job ID: 135671049