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Job Description

IMCBs JG Lab is seeking a highly motivated and talented Research Fellow to join a competitive, interdisciplinary research programme on advanced cancer biology. The successful candidate will play a key role in executing cutting-edge cancer proteomics analyses, and integrated validation using cell, spatial, and translational biology approaches.

This position offers the opportunity to work at the interface of state-of-the-art proteomics, spatial biology, and clinical translation, within a vibrant, highly collaborative research environment.

Key responsibilities:

  • Design, execute, and interpret advanced proteomics analyses (both Mass Spectrometry (MS) and Non-MS), including targeted and untargeted approaches.
  • Develop, optimize, and implement novel proteomics workflows/technologies for actionable proteome analysis.
  • Perform biological and translational validation of proteomics findings using: Clinical samples, cell culture, organoid, and/or animal models Biochemical, molecular, and spatial biology assays
  • Conduct imaging- and mechanics-based validation, including techniques such as SHG, AFM or related modes.
  • Contribute to and support assay and prototype development for functional and translational readouts.
  • Handle and manage clinical samples, ensuring compliance with regulatory and ethical requirements.
  • Prepare scientific reports, presentations, and manuscripts, and contribute to grant-related activities where appropriate.
  • Train junior researchers and students when needed
  • Work closely with the lead PI, collaborating PIs, clinicians, and interdisciplinary teams across proteomics, spatial biology, and cancer research themes.
  • Undertake related administrative and project coordination duties as required.

Requirements

  • PhD in Biochemistry, Biology, Chemistry, Proteomics or related life sciences field
  • Hands-on experience in advanced MS-based proteomics, biological validations and spatial proteomics (plus)
  • Experience with clinical samples, biochemical assays and imaging preferred
  • 2+ years of postdoc experience in the related area/s with a track record is a plus

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About Company

The Agency for Science, Technology and Research (A*STAR) is a statutory board under the Ministry of Trade and Industry of Singapore.The agency supports R&D that is aligned to areas of competitive advantage and national needs for Singapore. These span the four technology domains of Manufacturing, Trade and Connectivity, Human Health and Potential, Urban Solutions and Sustainability, and Smart Nation and Digital Economy set out under the nation's five-year R&D plan (RIE2025).

Job ID: 144402955