Research Fellow (Mechanobiology Institute)

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Job Description

The Mechanobiology Institute (MBI), Singapore, is a multidisciplinary institute committed to developing new paradigms for biomedical research by focusing on the quantitative analysis of dynamic functional processes. Through quantitative biophysical approaches, we address major problems in biomedical sciences, including pathogenesis (from bacterial to cancer), tissue regeneration, and function

The research team of Asst. Prof. Natalie Dye seeks a highly motivated and talented young scientist to join their laboratory studying the biophysical mechanisms of epithelial tissue growth and morphogenesis as a postdoctoral fellow.

Project Scope

The successful candidate will work on a research project dedicated to understanding how animal cells collectively build 3D tissue architectures, either in vivo or ex vivo. The project involves using advanced light microscopy methods, quantitative bioimage analysis, and biophysical methods to probe the mechanisms that organize collective cell dynamics at the tissue scale. While the group has worked extensively with the Drosophila wing as a model tissue, they are also branching out into other tissues in the fly, as well as ex vivo cell/organoid models.

The position offers the opportunity to shape a new project in a relatively new team - the group having moved to the MBI at the end of 2024. At the same time, the team is imbedded within the well-established MBI at NUS, which offers an open, interactive, and interdisciplinary research environment. In this environment, the successful candidate will have the possibility to hone project management skills and gain teaching/mentoring/leadership experience. As well, he/she will be exposed to other world-class research on diverse topics through regular scientific seminars and have access to excellent facilities.

Qualifications

• Candidates should hold undergraduate and PhD degrees (or be in the final stages of obtaining their PhD) in life sciences, biophysics, or a related field
• Previous publications, at least in preprint, demonstrating the candidate's skills and ability to complete a project are strongly preferred
• Experience working with model organisms, especially Drosophila and/or mouse/human organoids/iPSCs, is ideal
• Experience performing modern microscopy experiments (e.g., confocal and light sheet) and/or programmatic bioimage analysis (ideally Python) and/or bioinformatics is required
• Candidates should be able to demonstrate excellent communication and presentation skills
• Candidates should be comfortable working both independently and in a team, be highly motivated, and be willing to take initiative
• Strong interest in working in an interdisciplinary environment at the interface of cell/developmental biology, physics and medicine is a must

Salary and benefits are commensurable to educational qualifications and working experience of the candidates.

To Apply

Interested candidates should prepare to submit

1. A cover letter describing their general research experience/interests and their motivation to apply to this position specifically,
2. CV, including a full publication list (ideally containing doi links),
3. The names and contact information of 2-3 references.

Applications will be evaluated upon submission on a rolling basis until the position is filled. Only shortlisted candidates will be contacted. Questions about the position can be directed to .