Research Fellow (CIRC)

Interested applicants are invited to apply directly at theNUS Career Portal. Please note your application will only be processed if youapply via NUS Career Portal.

NUS Career Portal link: https://careers.nus.edu.sg/job/Research-Fellow-%28CIRC%29/28589-en_GB/st=FCA72A7D0B9BD455C6D15EC35EEE3B70C68BEF40

We regret that only shortlisted candidates will be notified.

Job Description

The National University of Singapore invites applications for the position of Research Fellow in the Department of Clinical Imaging Research Centre (CIRC), Yong Loo Lin School of Medicine. CIRC is a dedicated molecular imaging research centre, equipped with state-of-the-art, GMP-certified facilities for the on-site production of PET and theransotics radiopharmaceuticals, as well as the development of novel molecular imaging probes. CIRC is positioned to support both academic and commercially led clinical research programs, with dedicated clinical imaging facilities area for advanced modalities of PET-CT and PET-MRI.

We are seeking an experienced Research Fellow to manage and oversee cutting-edge research in the development of radiopharmaceuticals. In this pivotal role, you will guide a team of radiochemists and researchers, manage complex radiochemistry projects, and contribute to the advancement of innovative treatments for medical imaging and cancer therapy. You will oversee the development, optimization, and validation of radiochemical processes, while ensuring compliance with regulatory standards and fostering a culture of scientific excellence within the laboratory.

Purpose of the post
The Research Fellow will be an essential staff leading the development of radiopharmaceuticals, including focusing on innovative strategies for diagnostic and therapeutic applications. Assisting in the development of new radiochemical synthesis methods and new molecular imaging probes

Main Duties and Responsibilities

The Research Fellow will be able to:

. Leadership & Team Management: Lead and mentor a team of radiochemists and research scientists, manage complex radiochemistry projects, and contribute to the advancement of innovative treatments for medical imaging and cancer therapy. Able to provide technical expertise, career development, and performance management. Promote a collaborative and high-performance work environment.

. Research & Development: Drive the design, synthesis, and characterization of novel radiopharmaceuticals, focusing on innovative strategies for diagnostic and therapeutic applications. Oversee the development and optimization of radiochemical methodologies and perform routine production of radiopharmaceuticals using automated radiochemistry synthesis modules to carry out radioisotope incorporation (e.g., F-18, C-11) and radiotracer formulation. Assisting in the development of new radiochemical synthesis methods and new molecular imaging probes.
. Project Management: Manage and prioritize multiple research projects, ensuring timely completion within budget and in alignment with the company's strategic goals. Develop project plans, timelines, and resource allocation strategies.
. Regulatory Compliance: Ensure compliance with regulatory standards, including cGMP, FDA, EMA, and other relevant standards. Lead efforts for the preparation and submission of regulatory documentation for new radiopharmaceutical products and foster a culture of scientific excellence within the laboratory.
. Collaboration: Work closely with cross-functional teams, including clinical development, manufacturing, quality assurance, and external collaborators, to ensure successful translation of research findings to clinical applications.
. Innovation & Process Optimization: Identify and implement new technologies, techniques, and methodologies to improve the efficiency and quality of radiopharmaceutical production. Continuously seek opportunities for innovation in radiochemistry and radiopharmaceutical manufacturing.
. Publications & Presentations: Author and present scientific publications in peer-reviewed journals and at industry conferences. Represent the company at scientific meetings, fostering relationships with key opinion leaders in the field.
. Laboratory Management: Assist in writing of SOPs, involved in routine maintenance of laboratory equipment, maintaining a clean and safe laboratory environment and any ad hoc duties as required for this role.
. Budget Management: Manage the research budget, ensuring efficient allocation of resources. Oversee the procurement of necessary materials, equipment, and supplies.

Qualifications

. Education: PhD in Radiochemistry, Chemistry, Pharmaceutical Sciences, or a related field.
. Experience: Minimum of 5-10 years of hands-on experience in radiopharmaceutical research and development, with at least 3-5 years in a management or leadership role.
. Expertise: In-depth knowledge of radiochemical synthesis, purification techniques, and characterization methods for radiopharmaceuticals. Expertise in GMP practices and regulatory compliance is required.

. Technical Skills: Proficient in radiochemical instrumentation and analytical techniques (e.g., HPLC, TLC, gamma spectroscopy). Familiarity with drug development and clinical trial processes is a plus.

. Problem-Solving: Strong analytical and problem-solving skills, with the ability to troubleshoot complex issues in radiochemical processes and product development.
. Innovation: A passion for scientific innovation and a drive to push the boundaries of radiopharmaceutical development.

Personal Attributes:

. Strong leadership and team-building capabilities.
. Excellent communication skills, both written and verbal.
. Detail-oriented, with a focus on quality and accuracy.
. Ability to thrive in a fast-paced, dynamic work environment.

Preferred Qualifications:

. Experience in the commercialization of radiopharmaceuticals.
. Familiarity with the clinical application of radiopharmaceuticals in oncology or neurology.
. Industry experience in an FDA-regulated environment or similar.

Application

Remuneration will be commensurate with the candidate's qualifications and experience. Informal enquiries are welcome and should be made to Miss Emmalyn Chan Mei Mei at [Confidential Information].

Formal application: Please submit your application, indicating current/expected salary, supported by a detailed CV (including personal particulars, academic and employment history, complete list of publications/oral presentations and full contacts of three (3) referees to this job portal.

We regret that only shortlisted candidates will be notified.