Research Fellow (Biological Sciences)

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Job Description

The Department of Biological Sciences (DBS), National University of Singapore (NUS), is seeking a highly motivated Research Fellow (Postdoctoral Researcher) in the area of bacterial immunity

The successful candidate will work on CRISPR-based bacterial immune systems and host-phage interactions, with the goal of understanding molecular mechanisms and developing new genome engineering applications. The position will involve independent experimental work, data analysis, manuscript preparation, and collaboration within an active and well-funded research environment

The anticipated start date is December 2025.

Qualifications

PhD in Molecular Biology, Biochemistry, Microbiology, Structural Biology, Synthetic Biology, or a closely related field.

• Candidates who have already passed their PhD defense and are awaiting formal conferment are also eligible

Skills:

• Excellent experimental ability in bacterial genetics and bacterial physiology.
• Proven proficiency in protein expression and purification (bacterial and/or mammalian expression systems), and downstream biochemical/biophysical assays.
• Strong hands-on skills in molecular cloning, genome editing, and in vitro reconstitution of protein-nucleic acid complexes.
• Confident in designing and executing cell-based assays (e.g. functional readouts, viability assays, reporter systems).
• Able to independently design experiments, troubleshoot, and interpret complex datasets.
• Strong scientific writing and presentation skills in English.

Experience:

• Demonstrated research excellence with 3 first-author publications in high-impact journals (impact factor 10.
• Extensive, direct bench experience (not only supervision) in bacteria work, protein purification, biochemical characterization, and cell-based experiments.
• Evidence of scientific independence: ability to drive a project from concept to publication with minimal day-to-day supervision.